Research Articles
Mycoplasma Contamination in Stem Cell Culture: Prevention, Detection, and Control Strategies for Researchers
This article provides a comprehensive guide for researchers and drug development professionals on addressing mycoplasma contamination in stem cell cultures.
Karyotype Monitoring in Stem Cells: A Comprehensive Guide to Detecting and Managing Genetic Instability for Research and Therapy
Genetic instability in stem cells, particularly induced pluripotent stem cells (iPSCs), poses a significant challenge to their research validity and therapeutic safety.
Overcoming Immune Rejection in Stem Cell Therapies: From Foundational Mechanisms to Clinical Applications
This article provides a comprehensive analysis of the immunological barriers and evolving immunosuppression strategies in stem cell-based therapies.
Mitigating Teratoma Risk in Stem Cell Therapies: 2025 Strategies for Detection and Safety
This article provides a comprehensive analysis of teratoma formation, a critical tumorigenicity risk associated with pluripotent stem cell (PSC)-derived therapies.
Designing Stem Cell Clinical Trials: A Phase-by-Phase Guide from IND to BLA
This article provides a comprehensive guide to the design and execution of Phase I, II, and III clinical trials for stem cell-based therapies.
CRISPR-Engineered Stem Cells: Revolutionizing Therapeutic Development and Disease Modeling
This article provides a comprehensive analysis of the integration of CRISPR gene editing with stem cell technology, a frontier that is reshaping biomedical research and therapeutic development.
Hydrogel Scaffolds for Stem Cell Delivery: Engineering the Microenvironment for Enhanced Regenerative Therapy
This article provides a comprehensive analysis of hydrogel-based scaffolds as advanced delivery systems for stem cells in regenerative medicine.
In Vivo Stem Cell Tracking: Imaging Techniques for Monitoring Therapeutic Efficacy and Safety
Stem cell therapies hold immense clinical potential for treating conditions from cardiovascular disease to neurological disorders.
Advanced Cryopreservation Protocols for Stem Cell Banking: A Comprehensive Guide for Research and Clinical Translation
This article provides a comprehensive analysis of modern stem cell cryopreservation, storage, and quality control protocols tailored for researchers and drug development professionals.
Stem Cell Secretome Characterization and Exosome Isolation: A Comprehensive Guide for Translational Research
This article provides a comprehensive overview of the current landscape, methodologies, and challenges in stem cell secretome and exosome research.